Shankargouda Patil, BDS, MDS (Oral & Maxillofacial Pathology), PhD, FRCPath, FDS RCPS (Glasg), FICD and FPFA

Professor

Area of expertise

Immunobiology, Oral Pathology, Oral Microbiology, Oral Oncology, Translational Oncology, Artificial Intelligence ,Digital Dentistry,四色AV Pulp Stem Cells, Molecular biology, Molecular Oncology, Periodontal Medicine

Dr. Shankargouda Patil received his PhD in Medical Biotechnology from University of Siena, Italy. His thesis subject was on the effect of water pipe smoking (tobacco) on oral keratinocytes. His formative research training and experience at Hong Kong university has prepared him to be an ethical and effective researcher. He has been an academic supervisor and held the position of Associate Professor at Jazan University from 2016 to 2022. He holds a visiting professorship at the University of Siena, Department of Oral Pathology, School of 四色AV Medicine, Siena, Italy and in as a distinguished visiting professor at the Centre of Molecular Medicine and Diagnostics (COMManD) at Saveetha University, India.

Dr. Patil is an internationally acknowledged expert in translational research, Oral Potentially Malignant Disorders and Oral Cancer. In his career as a dental educator and academician, Dr. Patil has published numerous peer-reviewed articles on oral oncology and oral pathology which have received over 7000 citations. He has contributed to numerous textbooks. He serves on the Editorial Board of several prestigious journals. Based on data from Standford University, he is placed in the top 2% of scientists in the world across all disciplines. He is a sought after speaker at national and international forums and conferences for this expertise in the field.

Education:

PhD. in Medical biotechnology from University of Siena, Italy
MDS in Oral & Maxillofacial Pathology from Sree Balaji 四色AV College, Chennai, India
BDS in 四色AV Surgery from PMNM 四色AV College & Hospital, Bagalkot, India

Research Interest:

Cancer stem cell biology in premalignant and malignant oral lesions, Inflammation biology in oral diseases, Dynamics of dental pulp mesenchymal stem cells (DPSCs) differentiation, Genomics and proteomics of oral diseases caused by tobacco
products

Affiliation:

Member of Global Burden of Disease Collaborative Network by University of Washington
Fellowship of the Royal College of Pathologists (UK)
Membership of the Faculty of 四色AV Surgery, Royal College of Physicians and Surgeons (Glasgow, UK)
Fellow of International College of Dentists
Fellow of the Pierre Fauchard Academy
Fellow of the Academy of General Education (Manipal, India)
Editor-in-Chief: The Journal of Contemporary 四色AV Practice (JCDP) www.thejcdp.com
Editor-in-Chief: World Journal of Dentistry (WJD) www.wjoud.com
Editor for the special issue 鈥楢dvance Research on Molecular Oral Microorganism鈥 in the journal Current Issues in Molecular Biology
Editor for the special issue 鈥楽creening diagnosis and treatment of Oral Cancer鈥 in the journal Life
Editor for the special issue 鈥楥urrent concepts and prospects of diagnostics in oral diseases鈥 in the journal Diagnostics
Editorial board member: Clinical Oral Investigations
Editorial board member: BMC Research Notes
Advisory board member:Heliyon

Awards:

Best peer-reviewer Award by Publons/Web of Science in 2019
Awarded for Highest number of impact factor papers in Jazan University 2021
Based on data from Standford University, placed in the top 2% of scientists in the world across all disciplines in 2021

Subjects Taught:

Oral pathology, Oral medicine, Oral Oncology, General histology, General Pathology, Biomedical sciences, Basic sciences, Research and Publishing

Research Publications:

1. Mathew R, Palatinus S, Padala S, Alshehri A, Awadh W, Bhandi S, Thomas J, Patil S. Neural networks for classification of cervical vertebrae maturation: a systematic review. Angle Orthod. 2022 Sep 7. doi: 10.2319/031022-210.1

2. Pushpalatha C, Dhareshwar V, Sowmya SV, Augustine D, Vinothkumar TS, Renugalakshmi A, Shaiban A, Kakti A, Bhandi SH, Dubey A, Rai AV, Patil S. Modified Mineral Trioxide Aggregate-A Versatile 四色AV Material: An Insight on Applications and Newer Advancements. Front Bioeng Biotechnol. 2022 Aug 9;10:941826. doi: 10.3389/fbioe.2022.941826

3. Panigrahi DP, Patra S, Behera BP, Behera PK, Patil S, Patro BS, Rout L, Sarangi I, Bhutia SK. MTP18 inhibition triggers mitochondrial hyperfusion to induce apoptosis through ROS-mediated lysosomal membrane permeabilization-dependent pathway in oral cancer. Free Radic Biol Med. 2022 Aug 16:S0891- 5849(22)00547-0. doi: 10.1016/j.freeradbiomed.2022.08.019

4. Patra S, Patil S, Das S, Bhutia SK. Epigenetic dysregulation in autophagy signaling as a driver of viral manifested oral carcinogenesis. Biochim Biophys Acta Mol Basis Dis. 2022 Aug 5;1868(11):166517. doi: 10.1016/j.bbadis.2022.166517

5. Debta P, Swain SK, Sahu MC, Abuderman AA, Alzahrani KJ, Banjer HJ, Qureshi AA, Bakri MMH, Sarode GS, Patro S, Siddhartha S, Patil S. Evaluation of Candidiasis in Upper-Aerodigestive Squamous Cell Carcinoma Patients-A Clinico-Mycological Aspect. Int J Environ Res Public 四色AV. 2022 Jul 12;19(14):8510. doi: 10.3390/ijerph19148510

6. Nishanthine C, Miglani R, R I, Poorni S, Srinivasan MR, Robaian A, Albar NHM, Alhaidary SFR, Binalrimal S, Almalki A, Vinothkumar TS, Dewan H, Radwan W, Mirza MB, Bhandi S, Patil S. Evaluation of Fluoride Release in Chitosan-Modified Glass Ionomer Cements. Int Dent J. 2022 Jul 6:S0020- 6539(22)00107-1. doi: 10.1016/j.identj.2022.05.005

7. Sujatha G, Veeraraghavan VP, Alamoudi A, Bahammam MA, Bahammam SA, Alhazmi YA, Alharbi HS, Alzahrani KJ, Al-Ghamdi MS, Alzahrani FM, Varadarajan S, Raj AT, Patil S. Role of Toothbrushes as Gene Expression Profiling Tool for Oral Cancer Screening in Tobacco and Alcohol Users. Int. J. Environ. Res. Public 四色AV 2022, 19, 8052. https://doi.org/10.3390/ijerph19138052

8. Patil S, Alzahrani KJ, Banjer HJ, Halawani IF, Alzahrani H, Altayar MA, Albogami S, Angeles RF, Hassan AA, Bhandi S, Raj AT. Receptor Binding Domain of SARS-CoV-2 from Wuhan Strain to Omicron B.1.1.529 attributes increased affinity to variable structures of Human ACE2. J Infect Public 四色AV. 2022. doi: https://doi.org/10.1016/j.jiph.2022.06.004

9. Kamat MS, Puranik RS, Das Rai AB, Patil BR, Patil S. Assessing immuno-expression of p53 protein and TP 53 gene amplification in histologically negative surgical margins of oral squamous cell carcinoma patients and normal oral mucosa. Clin Oral Investig. 2022 Jun 8. doi: 10.1007/s00784-022-04574-y

10. Bhol CS, Mishra SR, Patil S, Sahu SK, Kirtana R, Manna S, Shanmugam MK, Sethi G, Patra SK, Bhutia SK. PAX9 reactivation by inhibiting DNA methyltransferase triggers antitumor effect in oral squamous cell carcinoma. Biochim Biophys Acta Mol Basis Dis. 2022 May 6:166428. doi: 10.1016/j.bbadis.2022

11. Prasad M, Rajagopal P, Devarajan N, Veeraraghavan VP, Palanisamy CP, Cui B, Patil S, Jayaraman S. A comprehensive review on high fat diet-induced diabetes mellitus: An epigenetic view. J Nutr Biochem. 2022 May 6:109037. doi: 10.1016/j.jnutbio.2022.109037

12. Yadahalli R, Sarode GS, Sarode SC, Khan ZA, Vyas N, Kharat AH, Bhandi S, Awan KH, Patil S. CC group of chemokines and associated gene expression of transcription factors: Deciphering immunopathogenetic aspect of oral submucous fibrosis. Dis Mon. 2022 Mar 24:101351. doi: 10.1016/j.disamonth.2022.101351

13. Patil S, Al-Brakati A, Abidi NH, Almasri MA, Almeslet AS, Patil VR, Raj AT, Bhandi S CD44-positive cancer stem cells from oral squamous cell carcinoma exhibit reduced proliferation and stemness gene expression upon adipogenic induction. Med Oncol. 2022 Jan 4;39(2):23. doi: 10.1007/s12032-021-01617-4

14. Mahapatra KK, Mishra SR, Behera BP, Patil S, Gewirtz DA, Bhutia SK. The lysosome as an imperative regulator of autophagy and cell death. Cell Mol Life Sci. 2021 Oct 30. doi: 10.1007/s00018-021-03988-3

Presentations:

University of Illinois, Chicago – Cancer Stem Cells: Current concepts and Future prospects in 四色AV Research 鈥 5th July 2022
University of Illinois, Chicago – Introduction to 四色AV Research BME 462 Introduction to 四色AV Clinical/Research/ Technology – 20 April 2022